The brothers Fix & Foxi go through thick and thin together. When someone challenges them, the cheeky duo responds with clever ideas. The series is based on the successful comic series "Fix und Foxi", which started in 1953 and was one of the most successful German comic productions. Each episode consists of 4 shorts with Fix and Foxi and one with the "Peppercorn Family," which Rolf Kauka invented especially for the series. Prof. Knox has invented a flu remedy and is looking for a test person. Lupo is so sick that he even swallows this bitter pill, but Knox underestimated the side effects. Granny Eusebia's canary must be caught, but it is smarter than expected. Tricky Fix & Foxi are chasing it. Adventure in the snow: Lupo rushes off. Fix & Foxi try to stop him. Christmas preparations: Makiki is accused of snacking and suddenly disappears. The family is in great worry about her.